Mortality of Neonatal Respiratory Failure from Chinese Northwest NICU Network


Zhang et al, J Matern Fetal Neonatal Med. 2016 Sep  Abstract OBJECTIVES: We aimed to evaluate the efficacy of respiratory support and surfactant in incidence, management and outcome of neonatal respiratory failure (NRF) in Chinese emerging regional neonatal-perinatal care system in the era of universal health insurance policy. RESULTS: Among …

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MRI Evaluation and Safety in the Developing Brain


Tocchio et al, Semin Perinatol.  2015 Mar Abstract Magnetic resonance imaging (MRI) evaluation of the developing brain has dramatically increased over the last decade. Faster acquisitions and the development of advanced MRI sequences such as magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), perfusion imaging, functional MR imaging (fMRI), and susceptibility …

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Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants.


Darlow et al, Cochrane Database Syst Rev. 2016 Aug 22 Abstract BACKGROUND: Vitamin A is necessary for normal lung growth and the integrity of respiratory tract epithelial cells. Preterm infants have low vitamin A status at birth and this has been associated with an increased risk of developing chronic lung …

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Initial stabilisation of preterm infants: a new resuscitation system with low imposed work of breathing for use with face mask or nasal prongs


Donaldsson et al, Arch Dis Child Fetal Neonatal Ed. 2016 Aug 23. Abstract OBJECTIVE: T-piece resuscitation systems are pressure unstable and have high imposed work of breathing (iWOB). Pressure stable respiratorysupport with low iWOB might improve outcome. We have developed a new resuscitation system that can be used with nasal prongs …

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Synchronized mechanical ventilation for respiratory support in newborn infants.


Greenough et al, Cochrane Database Syst Rev. 2016 Sep (Cochrane review) Abstract BACKGROUND: During synchronised mechanical ventilation, positive airway pressure and spontaneous inspiration coincide. If synchronous ventilation is provoked, adequate gas exchange should be achieved at lower peak airway pressures, potentially reducing baro/volutrauma, air leak and bronchopulmonary dysplasia. Synchronous ventilation can …

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Consensus conference on the appropriateness of palivizumab prophylaxis in respiratory syncytial virus disease


Pignotti et al, Pediatr Pulmonol. 2016 Sep 12 Abstract Respiratory syncytial virus infection represents a clinical burden among young children under 24 months. Palivizumab is the only drug licensed in Italy for the prevention of serious lower respiratory tract disease requiring hospitalization caused by respiratory syncytial virus in children at high …

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Young Mother Kissing Infant

Iacovou et al, United European Gastroenterol J. 2015 Oct Introduction: Infantile colic is the most common complaint for which parents seek professional advice during the first months of life, and occurs in both breastfed and formula-fed infants. Mothers are often advised to avoid certain ‘gas-forming’ foods (e.g., onions or legumes) although …

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Distinguishing Arterial Ischemic Stroke From Hypoxic-Ischemic Encephalopathy in the Neonate at Birth


Adami et al, Obstet Gynecol. 2016 Sep 5 Abstract OBJECTIVE: To identify perinatal risk factors that can distinguish arterial ischemic stroke from hypoxic-ischemic encephalopathy at birth. METHODS: This is a cohort study of all neonates born at 35 weeks of gestation or greater admitted to our neonatal intensive care unit from …

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