“عظماء أبو الريش الراحلون من ظلمات صندوق النسيان إلى أضواء المعرفة والعرفان”

  السيدات والسادة الزملاء الأفاضل السلام عليكم ورحمة الله وبركاته،،،  وفاء للوعد الذى قطعه عل نفسه ا.د. صلاح نصار الأستاذ المتفرغ بقسم طب الأطفال بكلية طب قصر العينى – جامعة القاهرة، والخادم العاشق فى محراب “البيت الكبير”، فقد وفقنا الله سبحانه وتعالى، إلى وضع استرتيجية، وأهداف وخطة تنفيذ الكتاب، الذى…

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Ventilation in Extremely Preterm Infants and Respiratory Function at 8 Years

Doyle et al, N Engl J Med. 2017 Jul BACKGROUND: Assisted ventilation for extremely preterm infants (<28 weeks of gestation) has become less invasive, but it is unclear whether such developments in care are associated with improvemen ts in short-term or long-term lung function. We compared changes over time in the use of assisted ventilation and oxygen therapy…

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Delayed versus Immediate Cord Clamping in Preterm Infants

Tarnow-Mordi W et al, N Engl J Med. 2017 Dec BACKGROUND The preferred timing of umbilical-cord clamping in preterm infants is unclear.  METHODS The primary composite outcome was death or major morbidity (defined as severe brain injury on postnatal ultrasonography, severe retinopathy of prematurity, necrotizing enterocolitis, or late-onset sepsis) by 36 weeks…

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Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia

Bassler et at, N Engl J Med. 2018 Jan BACKGROUND : The long-term effects on neurodevelopment of the use of inhaled glucocorticoids in extremely preterm infants for the prevention or treatment of bronchopulmonary dysplasia are uncertain.  CONCLUSIONS   Among surviving extremely preterm infants, the rate of neurodevelopmental disability at 2 years did…

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Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials

Roth et al, BMJ, 2017 Abstract Objectives: To estimate the effects of vitamin D supplementation during pregnancy on 11 maternal and 27 neonatal/infant outcomes; to determine frequencies at which trial outcome data were missing, unreported, or inconsistently reported; and to project the potential contributions of registered ongoing or planned trials. Design: Systematic…

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Benign Neonatal Shudders, Shivers, Jitteriness, or Tremors: Early Signs of Vitamin D Deficiency

Collins & Young Pediatrics, July 2017 Abstract and tremors in the newborn period typically precipitate an extensive, invasive, and expensive search for the etiology. Vitamin D deficiency has not been historically included in the differential of tremors. We report a shivering, jittery newborn who was subjected to a battery of testing, with…

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Ventilator-Associated Pneumonia in Low Birth Weight Neonates at a Neonatal Intensive Care Unit: A Retrospective Observational Study

Lee et al, February 2017 Background Ventilator-associated pneumonia (VAP) is one of the most common healthcare-associated infections among ventilated patients. The aim of this study was to determine the clinical characteristics and risk factors for the development of VAP in intubated low birth weight (LBW) neonates in a neonatal intensive care…

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Bosentan as Adjunctive Therapy for Persistent Pulmonary Hypertension of the Newborn: Results of the Randomized Multicenter Placebo-Controlled Exploratory Trial.

Steinhorn et al, J Pediatr. 2016 Oct Abstract OBJECTIVE: To evaluate the efficacy, safety, and pharmacokinetics of the endothelin receptor antagonist bosentan as adjunctive therapy for neonates with persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN: This was a phase 3, multicenter, randomized, placebo-controlled exploratory trial (FUTURE-4). Eligible patients were >34 weeks gestation, <7 days old,…

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Risk Factors for Necrotizing Enterocolitis in Neonates: A Retrospective Case-Control Study

Lu et al, April 2017 Background Necrotizing enterocolitis (NEC) in neonates is devastating, and risk-factor identification is crucial. This study aimed to evaluate risk factors for NEC in different gestational age (GA) groups. Methods Risk factors associated with NEC were investigated using a retrospective case-control design.   Conclusion Intrahepatic cholestasis of…

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