Maternal and Placental Factors Associated with Congenital Hearing Loss in Very Preterm Neonates.

Kim et al, Pediatr Neonatol. 2017   BACKGROUND: Sensorineural hearing loss (SNHL) is a multifactorial disease that more frequently affects pretermnewborns. Although a number of maternal conditions have been reported to  be associated with preterm birth, little information is available concerning maternal risk factors for the development of SNHL. We aimed to identify maternaland placental risk factors associated with a “refer” result on the newborn hearing screening (NHS) test and subsequently confirmed SNHL in very preterm neonates.…

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Red Blood Cell Transfusion and Clinical Outcomes in Extremely Low Birth Weight Preterm Infants

Wang et al, Pediatr Neonatol. 2017  Background Red blood cell (RBC) transfusion is often considered a life-saving measure in critically ill neonates. The smallest and least mature  infants tend to receive the largest amount of transfusions. RBC transfusion itself has also been suggested as an independent risk facto r of poor…

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SIDS and Other Sleep-Related Infant Deaths: Updated 2016 Recommendations for a Safe Infant Sleeping Environment

TASK FORCE ON SUDDEN INFANT DEATH SYNDROME Pediatrics, October 2016, From the American Academy of Pediatrics, Policy Statement Abstract Approximately 3500 infants die annually in the United  States from sleep-related infant deaths, including sudden infant death syndrome (SIDS; International Classification of Diseases, 10th Revision [ICD-10], R95), ill-defined deaths (ICD-10 R99), and accidental…

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Impact of the US Maternal Tetanus, Diphtheria, and Acellular Pertussis Vaccination Program on Preventing Pertussis in Infants <2 Months of Age: A Case-Control Evaluation

Skoff et al, Clinical Infectious Diseases, September 2017   Abstract Background Infants aged <1 year are at highest risk for pertussis-related morbidity and mortality. In 2012, Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis) vaccine was recommended for women during each pregnancy to protect infants in the first months of life;…

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Risk of Autism Associated With Hyperbilirubinemia and Phototherapy

Wu et al, Pediatrics 2016 Abstract OBJECTIVE: Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder(ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy. CONCLUSIONS: After adjustment for the effects of sociodemographic factors and birth weight, neither hyperbilirubinemia nor phototherapy was an…

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Assessing the neuroprotective benefits for babies of antenatal magnesium sulphate: An individual participant data meta-analysis.

Crowther et al, PLoS Med. 2017 Abstract BACKGROUND: Babies born preterm are at an increased risk of dying in the first weeks of life, and those who survive have a higher rate of cerebral palsy (CP) compared with babies born at term. The aim of this individual par ticipant data (IPD) meta-analysis (MA)…

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Systematic Review of the Effect of Enteral Feeding on Gut Microbiota in Preterm Infants

Xu et al, J Obstet Gynecol Neonatal Nurs. 2017 Oct Abstract OBJECTIVE: To examine the effect of feeding type on microbial patterns among preterm infants and to identify feeding factors that promote the colonization of beneficial bacteria. Conclusion: Mothers’ own milk is considered the best form of nutrition for preterm infants and the gut microbial…

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Late (> 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst Rev. 2017 Oct, Doyle et al Abstract BACKGROUND: Many preterm infants who survive go on to develop bronchopulmonary dysplasia, probably as the result of persistent inflammation in the lun gs. Corticosteroids have powerful anti-inflammatory effects and have been used to treat individuals with established bronchopulmonary dysplasia. However, it is unclear whether any…

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