Gastro-Oesophageal Reflux and Apnoea: Is There a Temporal Relationship?

Rossor et al, Neona­tol­ogy 2018 Abstract Back­ground: Gas­tro-oesophageal reflux (GOR) and apnoea are com­mon in infants; whether there is a causal rela­tion­ship is con­tro­ver­sial.  Objec­tives: To deter­mine whether there  was a tem­po­ral rela­tion­ship between GOR and apnoea, in par­tic­u­lar, the fre­quen­cy of obstruc­tive apnoeas and if the fre­quen­cy of GOR episodes cor­re­lat­ed with…

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Low- versus High-Dose and Early versus Late Parenteral Amino-Acid Administration in Very-Low-Birth-Weight Infants: A Systematic Review and Meta-Analysis

Leen­ders et al, Neona­tol­ogy 2018 Abstract Objec­tives: Pro­vid­ing par­enter­al amino acids to very-low-birth-weight infants dur­ing the first weeks of life is crit­i­cal for ade­quate growth and neu­rode­vel­op­ment. How­ev­er, there is no con­sen­sus about what dose is appro­pri­ate or when to ini­ti­ate sup­ple­men­ta­tion. As a result, dai­ly prac­tice varies among neona­tal inten­sive care…

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Atraumatic versus conventional lumbar puncture needles: a systematic review and meta-analysis

Nath et al, The Lancet March 2018  Sum­ma­ry Back­ground Atrau­mat­ic nee­dles have been pro­posed to low­er com­pli­ca­tion rates after lum­bar punc­ture. How­ev­er, sev­er­al sur­veys indi­cate that clin­i­cal adop­tion of these nee­dles remains poor. We did a sys­tem­at­ic review and meta-analy­sis to com­pare patient out­comes after lum­bar punc­ture with atrau­mat­ic nee­dles…

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Human milk is perhaps the single most under-rated strategy to prevent bronchopulmonary dysplasia

Verd & Gino­vart, archdis­child-2018 Poets and Lorenz have pub­lished a thor­ough review on strate­gies (Arch Dis Child Fetal Neona­tal Ed 2018) like­ly to reduce bron­chopul­monary dys­pla­sia (BPD). They present an overview of the effec­tive­ness and safe­ty of inter­ven­tions backed by ran­domised con­trolled tri­als (RCT) and aimed at pre­vent­ing BPD. Their study con­cludes with…

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Afternoon napping during pregnancy and low birth weight: the Healthy Baby Cohort study

Song et al, Sleep Med. 2018 Apr 27 Abstract OBJECTIVE: Although after­noon nap­ping is very com­mon, par­tic­u­lar­ly in Chi­na, there are lim­it­ed data regard­ing the poten­tial health effects of after­noon nap­ping dur­ing preg­nan­cy on peri­na­tal out­comes. We aimed to inves­ti­gate the rela­tion­ship between after­noon­nap­ping dur­ing late preg­nan­cy and low birth weight (LBW). METHODS: A total of 10,111 women aged 15–50 years were recruit­ed from the ongo­ing Healthy Baby Cohort study in Chi­na, in 2012–2014.…

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Improved nutrition for extremely preterm infants — A population based observational study

West­in V, et al. Clin Nutr ESPEN. 2018. Abstract BACKGROUND AND AIMS: Extreme­ly preterm (EPT) infants are at high risk for mal­nu­tri­tion due to imma­tu­ri­ty and med­ical com­pli­ca­tions and they often accu­mu­late nutri­tion­al deficits and expe­ri­ence growth fal­ter­ing dur­ing treat­ment at neona­tal inten­sive care units (NICUs). Enhanced intake of ener­gy…

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Neonatal Hemodynamics: From Developmental Physiology to Comprehensive Monitoring

Vranck­en, et al, Front Pedi­atr. 2018 Apr (Depart­ment of Peri­na­tol­ogy (Neona­tol­ogy), Amalia Children’s Hos­pi­tal, Rad­boud Insti­tute for Health Sci­ences, Rad­boud Uni­ver­si­ty Med­ical Cen­ter, Nijmegen, Nether­lands) Main­te­nance of neona­tal cir­cu­la­to­ry home­osta­sis is a real chal­lenge, due to the com­plex phys­i­ol­o­gy dur­ing post­na­tal tran­si­tion and the inher­ent imma­tu­ri­ty of the car­dio­vas­cu­lar sys­tem…

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Management of term infants at increased risk for early-onset bacterial sepsis

Jef­feries, Pae­di­a­tr Child Health. 2017 Jul;22 (Cana­di­an Pae­di­atric Soci­ety, Fetus and New­born Com­mit­tee, Ottawa, Ontario) Back­ground Ear­ly-onset neona­tal bac­te­r­i­al sep­sis (EOS) has been defined as sep­sis occur­ring with­in the first sev­en days of life; most infants become symp­to­matic with­in 24 h of birth. EOS usu­al­ly results from ver­ti­cal trans­mis­sion and,…

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Effect of Atropine With Propofol vs Atropine With Atracurium and Sufentanil on Oxygen Desaturation in Neonates Requiring Nonemergency Intubation

A Ran­dom­ized Clin­i­cal Tri­al Dur­rmey­er, et al (the PRETTINEO Research Group) JAMA. 2018 Ques­tion  Does pre­med­ica­tion with propo­fol reduce the fre­quen­cy of pro­longed desat­u­ra­tion dur­ing naso­tra­cheal intu­ba­tion in neonates com­pared with the com­bi­na­tion of a rapid-onset short-act­ing opi­oid and a mus­cle relax­ant? Find­ings  In this ran­dom­ized clin­i­cal tri­al involv­ing 173…

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