Oral immunoglobulin for preventing necrotizing enterocolitis in preterm and low birth weight neonates

Fos­ter JP, Cole MJ, Seth R, 4 April 2016, Cochrane review Review ques­tion: Does the use of oral immunoglob­u­lin reduce the inci­dence of necro­tiz­ing ente­ro­col­i­tis and oth­er com­pli­ca­tions in preterm or low birth weight (or both) neonates? Back­ground: Immunoglob­u­lin giv­en oral­ly for pre­vent­ing emer­gency intesti­nal prob­lems (necro­tiz­ing ente­ro­col­i­tis) in pre­ma­ture and low birth weight new­born infants. Destruc­tive inflam­ma­tion…

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Risk Factors for Neurotoxicity in Newborns With Severe Neonatal Hyperbilirubinemia

Rasha Gamaleldin, Iman Iskan­der, Iman Seoud, Hanan Abo­raya, Alek­san­dr Aravkin, Paul D. Samp­son, Richard P. Wennberg, Pedi­atrics, Octo­ber 2011, VOLUME 128 / ISSUE 4   Abstract OBJECTIVE: To eval­u­ate the impor­tance of total serum biliru­bin (TSB) and neu­ro­tox­i­c­i­ty risk fac­tors in pre­dict­ing acute biliru­bin encephalopa­thy (ABE) at admis­sion or post­treat­ment biliru­bin encephalopa­thy (BE) in infants with severe hyper­biliru­bine­mia.…

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The effects of inhaled albuterol in transient tachypnea of the newborn

Kim et al, Aller­gy Asth­ma Immunol Res. 2014 Mar; Abstract PURPOSE: Tran­sient tachyp­nea of the new­born (TTN) is a dis­or­der caused by the delayed clear­ance of fetal alve­o­lar flu­id. β-adren­er­g­ic ago­nists such as albuterol (salbu­ta­mol) are known to cat­alyze lung flu­id absorp­tion. This study exam­ined whether inhala­tion­al salbu­ta­mol ther­a­py could improve clin­i­cal symp­toms in TTN.…

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Effects of ventilation on hearing loss in preterm neonates: Nasal continuous positive pressure does not increase the risk of hearing loss in ventilated neonates

Ras­to­gi et al, Int J Pedi­atr Otorhi­no­laryn­gol. 2013 Mar Abstract INTRODUCTION: There is increased risk of hear­ing loss in preterm neonates. This risk is fur­ther increased by envi­ron­men­tal noise expo­sure espe­cial­ly from life sup­port equip­ment such as ven­ti­la­tion. Nasal con­tin­u­ous pos­i­tive air­way pres­sure (NCPAP) used for res­pi­ra­to­ry sup­port of preterm neonates is…

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Short Maternal Stature Increases Risk of Small-for-Gestational-Age and Preterm Births in Low- and Middle-Income Countries

Indi­vid­ual Par­tic­i­pant Data Meta-Analy­sis and Pop­u­la­tion Attrib­ut­able Frac­tion. Kozu­ki et al, J Nutr. 2015 BACKGROUND: Small-for-ges­ta­tion­al-age (SGA) and preterm births are asso­ci­at­ed with adverse health con­se­quences, includ­ing neona­tal and­in­fant mor­tal­i­ty, child­hood under­nu­tri­tion, and adult­hood chron­ic dis­ease. OBJECTIVES: The spe­cif­ic aims of this study were to esti­mate the asso­ci­a­tion between short mater­nal stature and out­comes of…

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Patient-to-nurse ratios and outcomes of moderately preterm infants.

Prof­it et al, Pedi­atrics. 2010 Feb; Abstract OBJECTIVE: Mod­er­ate­ly preterm infants (30–34(6/7) weeks’ ges­ta­tion­al age) rep­re­sent the largest pop­u­la­tion of NICU res­i­dents. Whether their clin­i­cal out­comes are asso­ci­at­ed with dif­fer­ences in NICU nurse-staffing arrange­ments has not been assessed. The objec­tive of this study was to test the influ­ence of patient-to-nurse…

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Liver Failure in Early Infancy: Aetiology, Presentation and Outcome.

Bitar et al, J Pedi­atr Gas­troen­terol Nutr. 2016 Mar 21.   Abstract OBJECTIVE: Acute liv­er fail­ure (ALF) in ear­ly infan­cy is rare and chal­leng­ing to recog­nise and man­age. We aim to describe the pre­sen­ta­tion and out­come of infants with ALF accord­ing to their final aeti­ol­o­gy in order to elu­ci­date fea­tures…

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Lung Function at 8 and 16 Years After Moderate-to-Late Preterm Birth: A Prospective Cohort Study.

Thun­qvist et al, Pedi­atrics. 2016 Mar  Knowl­edge regard­ing lung func­tion after mod­er­ate­ly preterm birth is lim­it­ed. We there­fore inves­ti­gat­ed lung func­tion at ear­ly school age and ado­les­cence among chil­dren born mod­er­ate­ly preterm. RESULTS: At age 8 years, adjust­ed forced expi­ra­to­ry vol­ume in 1 sec­ond was low­er in preterm female sub­jects…

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Impact of antenatal steroids on intraventricular hemorrhage in very-low-birth weight infants.

Wei et al, J Peri­na­tol. 2016 Mar 24. Abstract OBJECTIVE: To deter­mine the asso­ci­a­tion between ante­na­tal steroids admin­is­tra­tion and intra­ven­tric­u­lar hem­or­rhage rates. RESULTS: In 25 979 very-low-birth weight infants, ante­na­tal steroid use was asso­ci­at­ed with a reduc­tion in inci­dence of any grade of intra­ven­tric­u­lar hem­or­rhage (odds ratio=0.68, 95% con­fi­dence inter­val: 0.62,…

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Fish oil supplementation improves pregnancy outcomes and size of the newborn: a meta-analysis of 21 randomized controlled trials.

Chen et al, J Matern Fetal Neona­tal Med. 2016 Jun Abstract OBJECTIVE: To observe the effects of fish oil on relat­ed preg­nan­cy out­comes. RESULTS: Twen­ty-one stud­ies com­pris­ing 10 802 preg­nant women were includ­ed. Dietary fish oil was asso­ci­at­ed with a 5.8-day increase in ges­ta­tion­al age of the new­born, a 22% reduced…

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