Efficacy of Antenatal Corticosteroid Treatment on Neurodevelopmental Outcome according to Head Circumference at Birth

Basset et al, Neonatology 2018 Abstract Background: There are concerns about the efficacy of antenatal corticosteroid treatment (ACT) in the growth-restricted fetus. Objective: To evaluate the effect of ACT on neurodevelopmental outcome at 2 years of corrected age according to the z score of birth head circumference (ZS HC) in…

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Temperature Probe Placement during Preterm Infant Resuscitation: A Randomised Trial

Bensouda et al, Neonatology 2018 Abstract Background: Hypothermia on admission to intensive care is associated with poor outcomes in preterm infants. The neonatal resuscitation program recommends the use of servo-control thermoregulation during resuscitation. Very little evidence exists to guide optimal temperature probe placement in the delivery room. Objective: The aim…

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The Impact of Maternal Gestational Hypertension and the Use of Anti-Hypertensives on Neonatal Myocardial Performance

Breatnach et al, Neonatology 2018 Abstract Background: Assessment of myocardial performance in neonates using advanced techniques such as deformation imaging and rotational mechanics has gained considerable interest. The applicability of these techniques for elucidating abnormal myocardial performance in various clinical scenarios is becoming established. We hypothesise that term infants born…

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First Trimester Vaginal Ureaplasma Biovar Colonization and Preterm Birth: Results of a Prospective Multicenter Study

Waldhoer et al, Neonatology 2018 Background: While there is a proven association of upper genital tract Ureaplasma infection during pregnancy with adverse pregnancy outcome, the effect of vaginal Ureaplasma colonization on preterm delivery has been controversially debated. Objectives: We hypothesized that women with isolation of vaginal U. parvum but not…

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Parenteral Nutrition in Critically Ill Children

Nilesh and Mehta, N Engl J Med 2016 Adequate nutrient delivery may help to offset the catabolic burden imposed by critical illness, preventing nutritional deterioration and improving outcomes. However, questions regarding the most appropriate dose of macronutrients, the route of delivery, and particularly the timing of supplemental parenteral nutrition in critically…

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Incidence of neonatal necrotising enterocolitis in high-income countries: a systematic review

Battersby et al, Arch Dis Child Fetal Neonatal Ed. 2018 Jan Abstract The early survival of preterm babies has increased in high-resource settings, and as a consequence, the number at risk of serious complications that commonly occur in the neonatal period, such as necrotising enterocolitis (NEC), is increasing. NEC is now one of the…

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Nasal High-Flow Therapy for Primary Respiratory Support in Preterm Infants

Roberts  et al, N Engl J Med. 2016 Sep  Abstract BACKGROUND: Treatment with nasal high-flow therapy has efficacy similar to that of nasal continuous positive airway pressure (CPAP) when used as postextubation support in neonates. The efficacy of high-flow therapy as the primarymeans of respiratory support for preterm infants with respiratory distress has not been proved.   CONCLUSIONS: When used as primary support for preterm infants with respiratory distress, high-flow therapy resulted in a significantly higher rate of treatment failure than did…

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