AlFaleh K, Anabrees J. Published Online: 10 April 2014
Necrotizing enterocolitis (NEC) and nosocomial sepsis are associated with increased and in preterm infants. Through prevention of bacterial migration across the , competitive exclusion of pathogenic bacteria, and enhancing the immune responses of the host, prophylactic enteral probiotics (live microbial supplements) may play a role in reducing NEC and the associated .
Enteral supplementation of probiotics prevents severe NEC and all cause in preterm infants. Our updated of available evidence strongly supports a change in practice. Head to head comparative studies are required to assess the most effective preparations, timing, and length of to be utilized.