Birth status, child growth, and adult outcomes in low- and middle-income countries

Stein et al, J Pediatr. 2013


OBJECTIVETo assess the impact of being born preterm or small for gestational age (SGA) on several adult outcomes.

RESULTS: Compared with those born term and at appropriate size for gestational age, schooling attainment was 0.44 years lower (95% CI, 0.17–0.71 years) in those born preterm and 0.41 years lower (95% CI, 0.20–0.62 years) in those born term but SGA.

CONCLUSIONBeing born preterm or term but SGA is associated with persistent deficits in adult height and schooling, but is not related to blood pressure or blood glucose level in low- and middle-income settings. Increased postnatal growth is associated with gains in height and schooling regardless of birth status, but not with increases in blood pressure or blood glucose level.