Risk of Autism Associated With Hyperbilirubinemia and Phototherapy

Wu et al, Pediatrics 2016

Abstract

OBJECTIVE:

Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder(ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy.

CONCLUSIONS:

After adjustment for the effects of sociodemographic factors and birth weight, neither hyperbilirubinemia nor phototherapy was an independent risk factor for ASD.