Risk of Autism Associated With Hyperbilirubinemia and Phototherapy

Wu et al, Pediatrics 2016



Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder(ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy.


After adjustment for the effects of sociodemographic factors and birth weight, neither hyperbilirubinemia nor phototherapy was an independent risk factor for ASD.