Nasal High-Flow Therapy for Primary Respiratory Support in Preterm Infants

Roberts  et al, N Engl J Med. 2016 Sep 



Treatment with nasal high-flow therapy has efficacy similar to that of nasal continuous positive airway pressure (CPAP) when used as postextubation support in neonates. The efficacy of high-flow therapy as the primarymeans of respiratory support for preterm infants with respiratory distress has not been proved.



When used as primary support for preterm infants with respiratory distress, high-flow therapy resulted in a significantly higher rate of treatment failure than did CPAP

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