A Multifaceted Approach to Improving Outcomes in the NICU: The Pediatrix 100 000 Babies Campaign

Ells­bury et al, Pedi­atrics, April, 2016 Abstract BACKGROUND AND OBJECTIVE: Despite advances in neona­tal med­i­cine, infants requir­ing neona­tal inten­sive care con­tin­ue to expe­ri­ence sub­stan­tial mor­bid­i­ty and mor­tal­i­ty. The pur­pose of this ini­tia­tive was to gen­er­ate large-scale simul­ta­ne­ous improve­ments in mul­ti­ple domains of care in a large neona­tal net­work through a…

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Effect of early low-dose hydrocortisone on survival without bronchopulmonary dysplasia in extremely preterm infants (PREMILOC): a double-blind, placebo-controlled, multicentre, randomised trial

Baud et al, Lancet, Feb­ru­ary, 2016 Abstract BACKGROUND: Bron­chopul­monary dys­pla­sia, a major com­pli­ca­tion of extreme pre­ma­tu­ri­ty, has few treat­ment options. Post­na­tal steroid use is con­tro­ver­sial, but low-dose hydro­cor­ti­sone might pre­vent the harm­ful effects of inflam­ma­tion on the devel­op­ing lung. In this study, we aimed to assess whether low-dose hydro­cor­ti­sone improved…

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Rumpel-Leede Phenomenon Associated With Tourniquet-like Forces of Baby Carriers in Otherwise Healthy Infants Baby Carrier Purpura

Naguyen et al, JAMA Der­ma­tol. 2016 Feb 17. A case report described acute-onset low­er-extrem­i­ty petechi­ae and pur­pu­ra caused by der­mal cap­il­lary rup­ture from a baby car­ri­er in oth­er­wise healthy infants (Rumpel-Leede phe­nom­e­non). Acute-onset, local­ized petechi­ae and pur­pu­ra of the low­er extrem­i­ties occurred in 3 oth­er­wise healthy infants fol­low­ing recent expo­sure to baby…

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Impact of Donor Milk Availability on Breast Milk Use and Necrotizing Enterocolitis Rates

Abstract OBJECTIVES: To exam­ine the avail­abil­i­ty of donor human milk (DHM) in a pop­u­la­tion-based cohort and assess whether the avail­abil­i­ty of DHM was asso­ci­at­ed with rates of breast milk feed­ing at NICU dis­charge and rates of necro­tiz­ing ente­ro­col­i­tis (NEC). METHODS: Indi­vid­ual patient clin­i­cal data for very low birth weight infants…

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Benefits of Delayed Cord Clamping in Red Blood Cell Alloimmunization

Garabe­di­an et al, Pedi­atrics, March, 2016 Abstract BACKGROUND AND OBJECTIVE: Sev­er­al stud­ies have shown the ben­e­fits of delayed cord clamp­ing (DCC) in preterm and in healthy new­borns at short and long term. Our objec­tive was to eval­u­ate the poten­tials ben­e­fits and risks of DCC in red cell alloim­mu­niza­tion. RESULTS: We…

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Videolaryngoscope for Teaching Neonatal Endotracheal Intubation: A Randomized Controlled Trial

Mous­sa et al, Pedi­atrics, March, 2016 Abstract OBJECTIVE: To assess whether the vide­o­laryn­go­scope (VL) is supe­ri­or to the clas­sic laryn­go­scope (CL) in acquir­ing skill in neona­tal endo­tra­cheal intu­ba­tion (ETI) and, once acquired with the VL, whether the skill is trans­fer­able to the CL. RESULTS: In phase 1, 34 pedi­atric res­i­dents…

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Total Duration of Breastfeeding, Vitamin D Supplementation, and Serum Levels of 25-Hydroxyvitamin D

Dar­mawikar­ta et al, Am J Pub­lic Health. 2016 Apr OBJECTIVES: To deter­mine the asso­ci­a­tion between total breast­feed­ing dura­tion and serum 25-hydrox­yvi­t­a­min D (25-OHD) and to explore whethervi­t­a­min D sup­ple­men­ta­tion influ­ences this asso­ci­a­tion. RESULTS: Each 1-month increase in total breast­feed­ing dura­tion was asso­ci­at­ed with a 0.12 nanograms per mil­li­liter low­er medi­an serum…

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Early Inhaled Budesonide for the Prevention of Bronchopulmonary Dysplasia

Bassler et al; Neu­ro­sis Tri­al Group, N Engl J Med. 2015 Study Sum­ma­ry Bron­chopul­monary dys­pla­sia (BPD) is a com­mon comor­bid con­di­tion among infants born at less than 28 weeks’ ges­ta­tion. Pre­vi­ous attempts to pre­vent the devel­op­ment of BPD using sys­temic cor­ti­cos­teroids have been effec­tive in reduc­ing BPD, but at the expense…

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Neuroprotection of Skin-to-Skin Contact (SSC)

Bergman, New­born & Infant Nurs­ing Reviews, 2015 Back­ground Skin-to-skin con­tact (SSC) gained promi­nence from the work of Rey and Mar­tinez, who relied on this prac­tice in the con­text of insuf­fi­cient incu­ba­tors. They showed that the “Kan­ga­roo Posi­tion” pro­vid­ed good phys­i­o­log­i­cal con­trol of very small neonates, that breast­feed­ing start­ed much ear­li­er pro­vid­ing…

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Prenatal exposure to antibiotics and wheezing in infancy: a birth cohort study

Popovic et al, Eur Respir J. 2016 Mar Abstract The role of pre­na­tal antibi­ot­ic expo­sure in the devel­op­ment of child­hood wheez­ing is debat­ed. We eval­u­at­ed whether this asso­ci­a­tion could poten­tial­ly be explained by con­found­ing factors.Antibiotic use in the first and third trimester of preg­nan­cy, wheez­ing in chil­dren aged ≤18 months and con­found­ing…

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