Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children


Scott, et al, JAMA Pediatr. January 9, 2017.  Abstract Importance  Improving emergency care of pediatric sepsis is a public health priority, but optimal early diagnostic approaches are unclear. Measurement of lactate levels is associated with improved outcomes in adult septic shock, but pediatric guidelines do not endorse its use, in part because …

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Maternal Preferences for Vitamin D Supplementation in Breastfed Infants


Umaretiya, et al, annals of family medicine, 2016 Abstract Daily vitamin D supplementation is recommended for breastfed infants, but alternative methods include enriching breast milk with vitamin D through maternal supplementation or intermittent high-dose vitamin D. We determined maternal preferences for vitamin D supplementation in 140 mothers with exclusively breastfed …

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Ventilator-Associated Pneumonia in Neonatal Patients: An Update


Cernada et al, Neonatology 2014 Abstract Ventilator-associated pneumonia (VAP) is a serious complication related to mechanical ventilation in the neonatal period. However, lack of a specific definition and difficulties obtaining noncontaminated samples of the lower respiratory airway render microbiological diagnosis and etiological treatment extremely difficult. Thus far, only few studies have …

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Comparing the Impact of Topical Application of Human Milk and Chlorhexidine on Cord Separation Time in Newborns


Abbaszadeh, et al, Pak J Med Sci. 2016 PAKISTANI STUDY Abstract Objectives: The best umbilical cord care after birth is a controversial issue. Aim of this research was to compare the effect of topical application of hu man milk and chlorhexidin on cord separation time in newborns. Conclusions: Topical application of …

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Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants


Editorial Group: Cochrane Neonatal Group14 December 2016 Abstract Background Chronic lung disease (CLD) occurs frequently in preterm infants. Bronchodilators have the potential effect of dilating small a irways with muscle hypertrophy. Increased compliance and tidal volume and decreased pulmonary resistance have been documented with the use of bronchodilators in infants …

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Longchain polyunsaturated fatty acid supplementation in preterm infants


Moon et al, Cochrane Neonatal Group, 20 December 2016 Abstract Background Controversy exists over whether longchain polyunsaturated fatty acids (LCPUFA) are essential nutrients for preterm infants because they may not be able to synthesise sufficient amounts of LCPUFA to meet the needs of the developing brain and retina. Objectives To assess whether …

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Breastfeeding for procedural pain in infants beyond the neonatal period


Harrison et al, 28 October 2016 Cochrane Pain, Palliative and Supportive Care Group Abstract Background Randomised controlled trials (RCTs) show that breastfeeding newbo rn infants during painful procedures reduces pain. Mechanisms are considered to be multifactorial and include sucking, skin-to-skin contact, warmth, rocking, sound and smell of the mother, and possibly …

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Association of Neurodevelopmental Outcomes and Neonatal Morbidities of Extremely Premature Infants With Differential Exposure to Antenatal Steroids

A baby girls feet being held the heart-shaped hands of her mother

Chawla et al,  JAMA Pediatr. 2016 Abstract Importance:  Many premature infants are born without exposure to antenatal steroids (ANS) or with incomplete courses. This study evaluates the dose-dependent effect of ANS on rates of neonatal morbidities and early childhood neurodevelopmental outcomes of extremely premature infants. Objective:  To compare rates of …

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